The Relative Potency between High Dose Oral Oxycodone and Intravenous Morphine
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چکیده
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the relationship between academic self-concept and academic achievement in english and general subjects of the students of high school
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BACKGROUND Oral opioid formulations contribute to postoperative analgesia. In this study, we evaluated the perioperative application of oral controlled-release oxycodone to reduce postoperative IV morphine consumption and opioid side effects after lumbar discectomy. METHODS Forty patients scheduled for elective lumbar discectomy over 1 or 2 levels were included in this prospective, randomized...
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Ultra-low-dose opioid antagonists have been shown to enhance opioid analgesia and alleviate opioid tolerance and dependence. Our present studies in male Sprague-Dawley rats assessed the abuse potential of oxycodone+ultra-low-dose naltrexone (NTX) versus oxycodone alone. The lowest NTX dose (1 pg/kg/infusion), but not slightly higher doses (10 and 100 pg/kg/infusion), enhanced oxycodone (0.1 mg/...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 1999
ISSN: 0885-3924
DOI: 10.1016/s0885-3924(99)00024-x